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Of the 371 shingles cases, 23% (87 individuals) had asthma, compared with 15% (114 of 742) from the control group. The authors found that adults with asthma were at about a 70% greater risk of developing shingles, compared to those without asthma. The researchers also noted that both asthma and atopic dermatitis were found to be independently associated with a higher risk of shingles. Researchers believe that, because asth ma helps suppress adaptive immunity, it may increase the risk of varicella zoster virus reactivation.
“As asthma is an unrecognised risk factor for zoster in adults, con ideration should be given to immunising adults aged 50 years and older with asthma or atopic dermatitis as a target group for zoster vaccination,“ Juhn noted. The researchers note that neither inhaled corticos teroids nor vaccinations were associated with a higher risk of shingles.
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