Diabetes-fighting `good fat' discovered
Scientists in Boston have
dis covered a new class of mole cules -produced in human
and mouse fat, with the equivalent of type 2 diabetes lowered their
elevated blood sugar. The higher levels of these lipids seem to be
associated with positive outcomes in mice and humans,“ said researcher
Barbara Kahn.
Lipids, like cholesterol, are typically associated
with poor health. But in recent years, researchers have discovered that
not all lipids are bad for you, such as the much touted Omega3 fatty
acids that are found in fish oils. The newly discovered lipids, called
fatty acid hydroxy fatty acids (FAHFAs) were lower in humans with early
stages of diabetes and were much higher in mice resistant to diabetes.
Once FAHFAs were identified as being the lipid that was different
between normal mice and these diabetes-resistant mice, the researchers
found something else important: when the mice eat FAHFAs, blood sugar
levels dropped and insulin levels rose, indicating the potential
therapeutic value of FAHFAs.
To determine whether FAHFAs are
also relevant in humans, the team measured FAHFA levels in humans who
are insulin-resistant (a condition which is often a precursor to dia
betes) and found that their FAHFA levels were lower in fat and blood,
suggesting that changes in FAHFA levels may contribute to diabetes.
These combined effects make the therapeutic potential of the lipids
tremendous, said the researchers.Besides, existing in low levels within a
wide range of vegetables, fruits and other foods, FAHFAs are also
-unlike the other known beneficial lipids -produced and broken down
inside the body.
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